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Structural characterization of the transporter protein TarG/H in wall teichoic acid biosynthesis of Gram positive bacterial pathogens
Staphylococcus aureus infections are a leading cause of healthcare and community associated infections worldwide. Some strains of…
View details2016Competition
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Structural Determinants of Kvl.5 Inactivation
Harley Kurata wants to contribute to the development of highly specific drugs with low toxicity for treating…
View details2001Competition
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Structural determination of bacterial type III secretion mechanisms
Overuse and improper use of common antibiotics have reduced their effectiveness because bacteria become resistant to the…
View details2003Competition
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Structural elucidation of glycosyltransferases: a target for novel antibiotics
Antibiotics have played a central role in treating bacterial infections ever since the introduction of penicillin. But…
View details2004Competition
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Structural exploration of locked nucleic acids (LNAs) for incorporation into anticancer oligonucleotides
Antisense oligonucleotides (AON) are short lengths of RNA or DNA molecules which are used to change gene…
View details2021Competition
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Structural valve degeneration in bioprosthetic heart valves
Bioprosthetic heart valves (BPHVs), valves made of biologic tissues rather than synthetic materials, have revolutionized the treatment…
View details2018Competition
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Structure and RNA-cleaving function of apurinic/apyrimidinic endonuclease 1 (APE1)
Cancer occurs when cells won’t stop growing. The source of this malfunction is often an alteration in…
View details2008Competition
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Structure-function relationship in smooth muscle contraction
Hollow organs such as the intestines, bladder, uterus, blood vessels, and the airways that make up lungs…
View details2006Competition
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Structure-function relationship of retinal guanylyl cyclase, a key enzyme in phototransduction
Light adaptation is the ability of visual system to adjust its performance to the ambient level of…
View details2024Competition
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Structure-function relationship of the GTP-exchange factor smgGDS and its role in breast cancer
Ras proteins act as molecular switches that control functions including growth and movement of all cells. They…
View details2001Competition
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