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Structural and functional correlates of neuroplastic change associated with stroke
In Canada, stroke is the third leading cause of neurological disease and death. Although improved acute care…
View details2013Competition
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Structural and Functional Investigation of Neuronal Calcium Channel Modulation
Cells contain highly complex protein structures that allow signals to be relayed from the outside environment using…
View details2024Competition
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Structural and functional investigation of skeletal muscle calcium channels in health and disease
For muscle contractions to occur, electrical signals will travel from the brain to the muscle via a…
View details2023Competition
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Structural and functional investigation of the skeletal muscle excitation-contraction coupling complex
This project aims to understand the basic function of the skeletal muscle, and how mistakes in this…
View details2023Competition
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Structural and Functional Studies of Peripheral Components of the Sec Translocase Supercomplex
The delivery of proteins to their correct cellular location is a fundamental aspect of cell biology. For…
View details2006Competition
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Structural and kinetic studies into eukaryotic sialyltransferases
The outer surfaces of mammalian cells are covered with a dense and complex array of sugar molecules.…
View details2008Competition
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Structural basis of novel strategies for the inhibition of AmpC-mediated beta-lactam antibiotic resistance in the opportunistic, nosocomial pathogen Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen often responsible for hospital-acquired infections, which can be very difficult…
View details2019Competition
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Structural basis of the glycerol-phosphate and the ribitol-phosphate chain polymerization in teichoic acid biosynthesis in rram-positive bacteria
One way of classifying bacteria is by their colour after applying a chemical stain (called the Gram…
View details2007Competition
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Structural characterization and inhibitor design of sialyltransfersases involved in lipooligosaccharide biosynthesis of Gram-negative pathogens
Bacterial resistance to antibiotics has become a major challenge in drug development. It is thus necessary to…
View details2004Competition
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Structural characterization of bacterial type III secretion system components
Bacterial resistance to antibiotics is on the rise and poses increasing threats to susceptible individuals, including the…
View details2002Competition
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Structural characterization of Propionibacterium acnes virulence factors
Acne is the most common skin disorder worldwide, affecting approximately 80 per cent of individuals at some…
View details2008Competition
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Structural characterization of the architecture and assembly of the bacterial type III secretion system injectisome
Gram-negative bacteria such as E.coli, salmonella, shigella, pseudomonas aeruginosa, and yersina pestis are responsible for a wide…
View details2013Competition
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