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Consequences of preconception bariatric surgery for fetal size and pathological growth restriction: a linked population registry study.
In Canada, 20-30% of reproductive-aged women suffer from obesity, which increases the chances that they will experience…
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Developing novel strategies to enhance CAR Treg manufacture and testing in transplantation
After organ transplantation, patients must take immunosuppressive drugs to prevent rejection of the organ by their immune…
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SuPA Mobility: Supporting Physical Activity for Mobility in Older Adults with Mobility Limitations
Problem As individuals age, they have a greater risk of limited mobility, or difficulty in getting around…
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Uncovering metabolic mechanisms for tumor-driven immunosuppression with mass spectrometry imaging
Scientists have uncovered ways to turn the body’s natural immune system against cancer – an approach termed…
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AI-based Platform for Ovarian Cancer Biomarker Discovery and Refinement
Ovarian cancer ranks fifth in cancer deaths among women. The revolution in our understanding of genetic and…
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Engineering Transfusable Platelets for Improved Hemorrhage Control
Failure to control bleeding, such as during trauma and childbirth, accounts for more than half of all…
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Gender equity through strengthening maternal nutrition and health in resource-limited settings
Rural, remote and marginalized people in areas of suboptimal healthcare service delivery are at increased risk of…
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Investigating oncogenic mechanisms in DICER1 syndrome-associated ovarian Sertoli-Leydig cell tumors
DICER1 syndrome is a rare, inherited disorder; individuals with a mutation (change) in the DICER1 gene are…
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Risk factors for cognitive impairment and substance-induced psychosis in people living in precarious housing or homelessness.
Social marginalization is a risk factor for poor health and is associated with psychotic and substance use…
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Use of CAR Tregs to induce transplantation tolerance
Organ transplantation, the primary treatment for organ failure, necessitates lifelong immunosuppressive therapy. Traditional immunosuppressants like steroids pose…
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A chemical biology approach to uncovering modulators of a Parkinson’s disease-linked protein
Enzymes are biological machines which facilitate crucial processes in the human body. A reduction in the function…
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Development of mutation-robust vaccines and antibodies, and their implications for the evolution of SARS-CoV-2
COVID-19 has caused over 774 million cases and 7.02 million deaths worldwide as of February, 2024. The…
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