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Impact of TSC2-deficient neural cells on microglial structure and function in an induced human pluripotent stem cell model of tuberous sclerosis complex
Tuberous sclerosis complex (TSC) is a rare genetic disease caused by mutations in the TSC2 gene. The…
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Integrating Exercise Snacks into Type 2 Diabetes Care: feasibility and management of cardiovascular risk factors
Most people living with type 2 diabetes (T2D) do not achieve enough physical activity and miss benefiting…
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Investigating the influence of residential green space on cognitive decline and dementia
The global population is aging rapidly. This demographic shift towards an older population poses a major public…
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Promoting the sustainability of digital interventions for sexually transmitted and blood-borne infections in Canda: A multi-methods study
More and more people are using digital tools to get tested for STIs. But we don’t know…
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Addressing inter-individual variability in aging: linking lifestyle factors to the brain and behaviour
Cognitive decline is associated with a variety of neurodegenerative disorders and is increasingly prevalent in Canada’s aging…
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Advancing Cardiovascular Research: Developing Vascularized Heart Organoids-on-Chips Integrating Immume Cells
Organoids, miniature organ models grown from stem cells, replicate the complexity of actual organs on a scale…
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Caregiver-Child Sleep and Relationships in Canadian Foster and Kinship Families
Sleep is important for health, yet little is known about sleep in foster and kinship families. In…
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Cerebrovascular physiology of circulatory death in patients undergoing medical assistance in dying (MAiD)
Patients undergoing medical assistance in dying (MAiD) can qualify as organ donors. Donation commences after death, which…
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Co-creation of culturally-safe drug checking practices for Indigenous Peoples who use illicit drugs
Indigenous Peoples who use illicit drugs (IPWUID) are disproportionately affected by the drug poisoning crisis. Community-wide drug…
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Structure-function relationship of retinal guanylyl cyclase, a key enzyme in phototransduction
Light adaptation is the ability of visual system to adjust its performance to the ambient level of…
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A personalized approach to non-physical practice after stroke
Chronic motor impairments are experienced by 85% of stroke survivors. Recovery of these impairments can be facilitated…
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Addressing antimicrobial resistance through the design and preclinical evaluation of a Klebsiella pneumoniae vaccine
Antibacterial resistance occurs when bacterial infections become resistant to treatment. It is a serious and growing threat…
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