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Characterization of Pathogenic Chromatin States in Synovial Sarcoma
Synovial sarcoma (SS) is the most common soft-tissue cancer among young adults. It is an aggressive tumor…
View details2020Competition
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Redevelopment and Optimization of an Adeno-Associated Virus Gene Therapy Product for the Treatment of Lipoprotein Lipase Deficiency
Lipoprotein lipase (LPL) is an enzyme that breaks down fats, specifically triglycerides, in the blood. An individual…
View details2020Competition
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Artificial intelligence based discovery of estrogen receptor activation function 2 (AF2) inhibitors as the first-in-class therapies for drug resistant breast cancers
Breast cancer (BCa) is the most common cancer and the second cause of death from cancer among…
View details2020Competition
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B cells: New players in the immune response to cancer
High-grade serous ovarian cancer is an aggressive disease with a low survival rate (~30%). Patients who survive…
View details2020Competition
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The Role of Microglia in Chronic Stress-Induced Cognitive Impairment
Chronic stress is associated with cognitive impairment. It is possible that this is due to the brain's…
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Developing novel therapeutic targets to treat arrhythmia-causing ryanodine receptor variants in the heart
Our hearts play a crucial role to distribute blood throughout our bodies. When it beats irregularly, also…
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Characterization of Gli proteins as a novel therapeutic target in prostate and breast cancer.
Prostate (PCa) and breast cancer (BCa) are leading causes of cancer deaths. These tumours depend on sex…
View details2020Competition
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Understanding adaptability in egg-laying behavior in Aedes aegypti
Mosquitoes are the deadliest animals on the planet. Aedes aegypti mosquitoes are found in many parts of…
View details2020Competition
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Determinants of sexual and reproductive health care for im/migrant women: a community-based mixed methods study to realize comprehensive primary care in BC
Primary care is key to a working health care system. Good primary care is based on relationships…
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Feeding patterns, nutrient status, and neurocognitive development in toddlers 18-24 months of age: A Randomised Control Trial
Early childhood represents a critical period in which a child’s brain undergoes rapid brain development and is…
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Using computational modeling to investigate the cognitive processes underlying behaviors related to gambling disorder in rats
Pathological gambling is an addictive disorder characterized by repeated problematic gambling despite severe negative consequences, often linked…
View details2020Competition
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Understanding counsellor-client interactions in spinal cord injury exercise counselling: a novel method to explain outcomes of randomized controlled trials by assessing intervention fidelity
Behavioural interventions often consist of conversations between counsellors and clients and can be a successful way to…
View details2020Competition
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