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Translational Proteomics and Systems Biology of Pediatric Malignancies
In Canada, cancer is the leading cause of disease-related death in children beyond the newborn period. Each…
View details2016Competition
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Translational TB Research: Identification of Novel Drug Targets and Development of Protective Vaccines
A recent report from the World Health Organization revealed that about 1.5 million people died from TB…
View details2008Competition
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Treatment of drug-resistant influenza: Rationally designed inhibitors of viral neuraminidase
Each year the influenza virus infects approximately 10% of the human population, resulting in hundreds of thousands…
View details2011Competition
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Treatment readiness and motivation research: improving quality of care and health outcomes
Treatment refusal, dropout, and relapse are common in individuals with eating disorders, resulting in physical and emotional…
View details2005Competition
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Uncovering novel regulators of beta cell genesis, growth and function
To date, the only successful approach for curing type 1 diabetes is to replace the insulin-producing beta…
View details2012Competition
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Understanding and disrupting fear memory in the brain
Fear memory, like that occurring in post-traumatic stress disorder, imposes pronounced health and financial burdens. Our laboratory…
View details2020Competition
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Understanding and exploiting genome instability in cancer
Cancer is caused by specific DNA mutations that can arise spontaneously over time. Conditions that increase DNA…
View details2016Competition
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Understanding and exploiting the role of phagocyte mechanobiology in anti-tumor immunity
Cancer is the leading cause of mortality in British Columbia. Whereas the immune system has long been…
View details2024Competition
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Understanding community capacity in mental health reform through an examination of the gendered dimensions of the Riverview redevelopment process in British Columbia
Recent mental health reforms in British Columbia have resulted in a shift in the way services are…
View details2005Competition
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Understanding how cationic antimicrobial peptides and lipopeptides function in order to design better antibiotics
With the ever-increasing prevalence of antibiotic resistance, it has become critical for scientists to develop alternatives to…
View details2008Competition
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Understanding human genome regulation through robust and multi-scale reference chromatin state annotations across hundreds of human cell types
Although researchers have identified tens of thousands of disease-associated genetic variants, the mechanisms driving most of these…
View details2021Competition
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Understanding service use decision-making and improving engagement among youth and young adults with mental health disorders
This program of research will seek to understand how youth and young adults (YYA) with mental health…
View details2019Competition
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