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Role of Myosin Va in trafficking of neuronal vesicles
Neurons (brain cells) are separated by gaps called synapses and communicate via mechanisms which enable them to…
View details2006Competition
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Role of notch signaling during endothelial to mesenchymal transformation
During heart development a subset of cells that line the inside of the heart, called endocardial cells,…
View details2005Competition
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Role of Notch-1 in Neurodegeneration and Neuroprotection
Alzheimer’s disease is a neurodegenerative disorder that causes deficits in memory, language and other cognitive functions. A…
View details2006Competition
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Role of Notch4 in angiogenesis
New blood vessels can grow from existing blood vessels in a process called angiogenesis. Limiting new blood…
View details2002Competition
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Role of Nrf2 mediated transcriptional events in neuroprotection during stroke
Free radicals are potentially damaging molecules produced in cells, particularly in response to injury. Certain free radicals…
View details2003Competition
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Role of oxidative stress in valproic acid-induced hepatotoxicity
Many patients with epilepsy take a drug called valproic acid to control seizures. Although the drug is…
View details2004Competition
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Role of PI3-kinase family in phagocytosis and phagosome maturation
Successful host defense against microorganisms relies heavily upon a population of immune cells called macrophages. These cells…
View details2002Competition
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Role of SASH1 in generation of hematopoietic stem cells
For many patients with a serious blood disorder or malignancy the primary treatment option is a stem…
View details2021Competition
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Role of sodium permeability and pore structure in determining differences in the rates of voltage dependent opening and closing in hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels
The pacemaker cells of the heart are a small group of cells that beat spontaneously and set…
View details2005Competition
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Role of TAK1 in resident fibro/adipogenic progenitors. A Key modulator of the inflammatory milieu and a therapeuthic target in chronic diseases
In our aging society, degenerative complications of chronic diseases are on the rise and account for a…
View details2019Competition
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Role of the Histone Acetyltransferases p300/CBP in Brown Adipose Tissue Adaptive Thermogenesis
Obesity is rising in Canada at an alarming rate, which is bad for our healthcare system because…
View details2019Competition
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Role of the Rap GTPases and the Pyk2 tyrosine kinase in B cell adhesion and spreading
B lymphocytes (B cells), which develop from stem cells in the bone marrow, are specialized immune cells…
View details2005Competition
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