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Bi-specific antisense and RNAi targeting of IGFBP-2 and IGFBP-5 as a novel treatment strategy for delaying progression and bony metastasis of prostate cancer
Prostate Cancer is the most common cause of cancer and the second leading cause of cancer death…
View details2003Competition
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Bidirectional genome-wide CRISPRi/a screening using ratiometric GCase substrates to identify genetic modulators of lysosomal GCase activity
Parkinson’s disease (PD) is a progressive brain disorder in which lysosomes—the cell’s waste-clearing system—do not function properly,…
View details2026Competition
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Bile Acid Malabsorption as a Driver of Epithelial Barrier Dysfunction in Crohn’s Disease
Crohn’s disease (CD) is a lifelong intestinal inflammatory disease, with a rapidly increasing prevalence. A common but…
View details2026Competition
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Biochemical and structural characterization of bacterial type III secretion system components
Harmful bacteria are becoming much more resistant to the currently available antibiotics, a situation that poses a…
View details2005Competition
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Bioengineering for the production of cells with islet function to treat Diabetes
A significant breakthrough in diabetes research occurred in 2000, when an Edmonton research group developed a protocol…
View details2005Competition
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Biogenesis of a lipid-modified autotransporter in Bordetella
The Bordetellae are respiratory pathogens that can cause severe infections in both humans and animals, including whooping…
View details2005Competition
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Bioinformatic analysis of large-scale microarry data
Dr. Karsten Hokamp is already known for developing the PubCrawler service used worldwide to stay up to…
View details2003Competition
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Bioinformatic and functional analysis of retroelements involved in the regulation of human genes
Josette-Renée Landry is bringing both computer science and traditional molecular biology techniques to her research into the…
View details2002Competition
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Bioinformatics of sequence indels: Novel applications for protein network analysis, drug target identification and drug development
Infectious diseases continue to be a huge threat worldwide. The effectiveness of current antibiotics is declining as…
View details2007Competition
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Biological pathways disrupted in mantle cell lymphoma pathogenesis
Mantle cell lymphoma (MCL) is an aggressive, incurable non-Hodgkin lymphoma with a median survival of three years.…
View details2006Competition
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Biological role of IL-7Ralpha Y449-dependent and -independent signals in T cell development and function
The molecule interleukin-7 (IL-7) is an important regulator of the development and signalling function of T cells,…
View details2008Competition
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Biomechanical energy harvesting
Electronic medical devices such as vital sign monitors, pacemakers and motorized prostheses are relied upon by people…
View details2007Competition
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