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Treating breast cancer with a novel programmable fusogenic gene delivery system for small interfering RNA targeting integrin-linked kinase
Cancer is a disease characterized by specific functional capabilities that are not typically expressed by normal healthy…
View details2008Competition
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Treatment adherence in first episode psychosis with a history of violence: understanding correlates and improving adherence
Research shows that if people who have experienced a first psychotic episode adhere to treatment, they are…
View details2004Competition
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Triggered release of anti-cancer drugs using hybrid lipid nanoparticle technology
Drugs used in cancer treatment, unfortunately, also can harm healthy cells. We’re working on a better way…
View details2024Competition
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Truncation of huntingtin and its relationship to the pathogenesis of Huntington's Disease
Huntington disease (HD) is a fatal degenerative brain disorder caused by a defective gene, which causes cells…
View details2003Competition
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Tying the gut in knots: Characterizing how pathogenic E. coli transform the gut cell landscape
Diarrheal disease affects 1.7 billion people every year, killing around 760,000 children. A leading cause of this…
View details2018Competition
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Uncoupling dopamine and glutamine transmission in animal models of schizophrenia
Schizophrenia affects one per cent of Canadians — more than 300,000 people — causing personality and perceptual…
View details2003Competition
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Uncovering cytoplasmic domains of NMDA receptors important for basal and activity-dependent trafficking to synapses
Glutamate receptors are important for excitatory transmission between neurons and for basic neural function, and the NMDA-type…
View details2006Competition
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Uncovering how specific “STAC” proteins regulate muscle contraction
Skeletal and heart muscle contraction requires calcium ions. Calcium ions enter muscle cells through 'calcium channels', which…
View details2019Competition
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Uncovering metabolic mechanisms for tumor-driven immunosuppression with mass spectrometry imaging
Scientists have uncovered ways to turn the body’s natural immune system against cancer – an approach termed…
View details2024Competition
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Uncovering the role of long non-coding RNA PAN3-AS1 in acute myeloid leukemia
In Canada, Acute Myeloid Leukemia (AML) presents a significant challenge, with only a 30% five-year survival rate…
View details2024Competition
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