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T Cell Therapy of Breast Cancer: Defining and Circumventing Barriers to T Cell Infiltration of the Tumour Microenvironment
T cells are white blood cells involved in a variety of our immune system responses, including detection…
View details2006Competition
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T regulatory cells and T helper 17 cells: interactions between two distinct T cell subsets important for immune homeostasis
The immune system tries to maintain an optimal balance between immune responses to control infection and tumour…
View details2007Competition
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T Regulatory cells in toxoplasma pathogenesis
Toxoplasma gondii, commonly acquired by eating under-cooked meat, is a particularly successful pathogen that establishes life-long infections…
View details2005Competition
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T-cell repertoire analysis for immune monitoring in renal transplantation
Kidney disease affects 1 in 10 Canadians with an estimated cost of over $2 billion per year.…
View details2021Competition
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Targeted isolation and identification of N-N bond-containing bioactive molecules from bacteria
In the modern pharmaceutical industrial, a large number of new drug candidates come from molecules isolated from…
View details2020Competition
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Targeting androgen receptor dimerization as a potential therapy for prostate cancer
Prostate cancer is a leading cause of death in men. Treatment involves reducing production of di-hydro-testosterone (DHT)…
View details2013Competition
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Targeting APOBEC3 enzymes as novel metabolic regulators in multiple myeloma
APOBEC3 are a family of molecules which mutate specific genes in the white blood cells of our…
View details2023Competition
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Targeting G Protein-Coupled Receptors to Improve Neurovascular Coupling in Alzheimer’s Disease
Alzheimer’s is a progressive disease that affects many Canadians. It causes problems with memory and thinking due…
View details2025Competition
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Targeting Lung Cancer Genomics: A Whole Genome Approach to Predicting Drug Response
Lung cancer is the leading cause of cancer death worldwide, with five-year survival rates among the lowest…
View details2007Competition
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Targeting neural transcription factor BRN2 in neuroendocrine tumours
One in eight men in Canada will be diagnosed with prostate cancer in their lifetime. Despite the…
View details2017Competition
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Targeting stress granules: A novel strategy to inhibit Ewing sarcoma metastasis
Metastatic disease remains the single most powerful predictor of adverse outcomes in Ewing sarcoma (ES) and other…
View details2017Competition
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Targeting the complement system in Alzheimer’s disease
Many seniors aged 65 or older experience “age-associated memory impairment,” a normal aging process. However, Alzheimer’s disease…
View details2018Competition
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