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Investigating the Role of the O-GlcNAc Post-Translational Modification in the Development of Type II Diabetes and Alzheimer's Disease
There is a growing prevalence of type 2 diabetes. It has been estimated that more than 20…
View details2007Competition
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Investigating what matters to youth: A mixed-methods study of youth-centred opioid treatments and their outcomes
Since 2016, approximately 1,200 youth in British Columbia (BC) between the ages of 15 and 24 have…
View details2021Competition
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Investigation into the factors mediating embryonic muscle migration in Caenorhaditis elegans
During embryonic development, precursor muscle cells (myoblasts) are generated in one region of the embryo and then…
View details2008Competition
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Investigation of aging-related pathways associated with an increased risk of emphysema in HIV-infected patients
Because antiretroviral therapy has enabled people to live longer, those with HIV now face a growing epidemic…
View details2013Competition
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Investigation of breast cancer genome heterogeneity in predictive models of drug action
A common method of testing new cancer drugs is to use human breast tumour cells that have…
View details2011Competition
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Investigation of genetic networks involving genes that confer chromosome stability in S. cerevisiae and C. elegans
Chromosomes are found in all organisms that have a cell nucleus, and carry the organism’s hereditary material.…
View details2008Competition
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Investigation of steroidogenesis mechanisms in prostate cancer progression: Effects of cytochrome P450 17A1 and steroid 5 alpha-reductase inhibitors
One in every eight Canadian men will be diagnosed with prostate cancer in their lifetime. Androgens, which…
View details2011Competition
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Investigation of the effects of floor stiffness on risk of fall-related hip fractures
About 23,000 people fracture their hips in Canada each year, resulting in treatment costs of approximately $1…
View details2004Competition
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Investigation of the factors secreted by feeders used in the maintenance of human embryonic stem cells
Embryonic stem cells can continually replicate themselves and also have the capacity to differentiate into other types…
View details2006Competition
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Investigation of the impact of HLA genetic diversity on HIV sequence evolution and clinical correlates of HIV disease
One of the major challenges facing HIV treatment and vaccine design is the virus’ capacity to mutate…
View details2006Competition
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Investigation of the Mechanisms of Hematopoietic Cell Generation from Human Embryonic Stem Cells
Human embryonic stem cells (ES cells) — cells obtained from an embryo when they are only a…
View details2007Competition
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Investigation of the molecular mechanisms of inactivation of the voltage-gated potassium channels Kv1.5 and Kv4.2
The strict regulation of our heart rates allows our bodies to adapt to changing conditions to provide…
View details2007Competition
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