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The Role of Presenilin Genes in Learning and Memory in C. elegans may Reveal Early Occurring Memory Deficits in Alzheimer's Disease
Jacqueline Rose aims to answer crucial questions about learning and memory loss associated with Alzheimer’s disease. In…
View details2001Competition
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The role of protein tyrosine phosphatase alpha (PTPa) in integrin signaling in fibroblasts
Communication between the outside and inside of cells relies on protein molecules (such as integrins) at the…
View details2005Competition
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The role of Raf-1 in pancreatic beta cell survival and insulin signaling
While we know that Type 1 diabetes is caused by the destruction of insulin-secreting beta-cells in the…
View details2009Competition
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The role of RyR2 in palmitate-induced beta-cell apoptosis in primary human and mouse pancreatic islets
Type 2 diabetes is a chronic disease affecting more than 2.2 million Canadians. The disease is characterized…
View details2007Competition
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The role of secreted protein acidic rich in cysteines (SPARC) in neurogenesis and gliogenesis in the embryonic and adult mouse brain: applications to models of Cerebral Ischemia Reperfusion Injury
Stroke is the primary cause of adult disability in Canada. Recovering brain function after stroke is dependent…
View details2008Competition
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The role of SHIP in normal and aberrant macrophage and osteoclast development and function
Michael Rauh believes the best approach to health research is to acquire insights from patients, and then…
View details2001Competition
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The role of SHIP in the development and function of myeloid immune suppressor cells
An important role of the immune system is to identify and eliminate tumour cells. When a tumour…
View details2008Competition
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The role of SHIP's C2 and PH domains in regulating hematopoietic cell growth and function
Various cancers and inflammatory diseases occur as a result of inappropriate activation of the body’s blood-forming hematopoietic…
View details2008Competition
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The role of social support in coping with chronic low back pain: help or hindrance?
Approximately 14 per cent of Canadians suffer from chronic low back pain, making it the second most…
View details2003Competition
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The role of specific genomic alterations in the aggressive nature of small cell lung cancer
Lung cancer remains the leading cause of cancer death for both men and women in Canada and…
View details2005Competition
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The role of the Ahi-1 oncogene in the regulation of hematopoietic stem cell development, function, and leukemogenesis
Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. The disease starts when genetic…
View details2011Competition
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The role of the airway epithelium NLRP3 inflammasome in asthma pathogenesis
Asthma is a respiratory disease that afflicts more than two million Canadians. Asthmatics experience both airway inflammation…
View details2011Competition
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