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Identification of Notch4-Modulated Genes in Vascular endothelia Cells
Graeme McLean’s research focuses on angiogenesis, the process by which a person’s existing blood vessels sprout extensions…
View details2001Competition
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Identification of novel apoptosis-related genes and pathways in cancers using bioinformatics approaches
Programmed cell death occurs when cells respond to internal or external signals by initiating a process that…
View details2002Competition
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Identification of novel genetic alterations in Lung Carcinogenesis
Lung cancer is the leading cause of cancer death in North America, with less than 15 percent…
View details2004Competition
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Identification of Phosphoregulation pathways involved in Hematopoetic Stem cell self-renewal
In recent years it has been suggested that hematopoietic stem cells (HSCs) possess the ability to develop…
View details2003Competition
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Identification of Positive Transcriptional Regulators of the tap-1 Gene
Worldwide in 2000, there were 10.1 million new cases of cancer, 6.2 million deaths due to cancer,…
View details2007Competition
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Identification of potential molecular markers and therapeutic targets involved in the progression of mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive cancer of the lymphatic system that is incurable with chemotherapy…
View details2004Competition
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Identification of Predictive Drug Response Signatures and Novel Resistance Genes by Whole Genome Profiling of Lung Tumors
Lung cancer causes more than a quarter of cancer deaths in Canada, with five-year survival rates among…
View details2007Competition
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Identification of predictive drug response signatures by whole genome profiling of lung tumors
Non-small cell lung cancer (NSCLC) accounts for an estimated 80% of known lung cancer cases. In many…
View details2005Competition
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Identification of proteolytic signatures elicited by allergen-derived proteases and their role in allergic sensitization
Allergic diseases are reaching epidemic proportions, now affecting 1 in 3 Canadians. Allergies are inappropriately high immune…
View details2018Competition
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Identification of regulatory mutations involved in cancer by gene expression analysis and bioinformatics approaches
Regulatory DNA sequences determine the leveI, location and timing of gene expression. These sequences are important in…
View details2006Competition
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Identification of sialyltransferase inhibitors and their use in the development of a chemical genetics tool for the study of normal and pathological cell surface carbohydrate modification
The complex arrangement of carbohydrates that cover the surfaces of cells is known to play a key…
View details2005Competition
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Identification of the mechanism and lineage responsible for the generation of bone marrow derived peripheral tissues
Bone marrow contains cells which infrequently contribute to the repair of numerous tissues and therefore holds tremendous…
View details2005Competition
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