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Endogenous cell replacement: progenitor characterization and promotion of oligodendrocyte differentiation and remyelination in the central nervous system by attenuating myelin inhibition
White matter is the part of the nervous system composed mainly of nerve fibres covered by a…
View details2008Competition
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Endothelial calcium dynamics regulating cerebrovascular function and capillary stalling in the healthy and diabetic brain
The brain is a metabolically demanding organ . Mismatch between blood flow and demand (from neurons) leads…
View details2021Competition
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Engagement and citizenship in long-term care: An exploration of resident and family councils
Resident and family councils refer to groups within long-term care (LTC) homes composed of residents and/or family…
View details2024Competition
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Engagement in opioid agonist therapy and risk for repeat overdose in people living with and without HIV who experienced a nonfatal opioid overdose: Providing insight to improve clinical care
The ongoing drug toxicity and overdose (OD) crisis has ruined the lives of many people in British…
View details2022Competition
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Engineering human immune organoids to study next-generation Treg transplant therapies
Organ transplant patients need strong, lifelong medications to prevent their immune systems from rejecting the new organ,…
View details2026Competition
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Engineering of carbohydrate processing enzymes for generation of therapeutic glycoproteins with increased serum halflife
Biopharmaceuticals are molecules produced using biotechnology, rather than chemistry, for therapeutic purposes. Biotechnology uses microorganisms (such as…
View details2008Competition
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Engineering of islets to produce the anti-diabetic hormone GLP-1
More than 2 million Canadians and 135 million people worldwide have diabetes, a chronic medical condition characterized…
View details2005Competition
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Engineering Platelets using therapeutic mRNA
Platelet cells are routinely transfused during treatment of a range of conditions, due to their specialized roles…
View details2021Competition
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Engineering stem cells to improve adaptive immune function
Thousands of Canadians receive bone marrow transplants each year to treat cancer and immune disease. Unfortunately, not…
View details2019Competition
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Engineering the design of regulatory T cell therapy in transplantation
Transplantation is a cure for end stage organ failure, but a successful transplant requires a life-long use…
View details2020Competition
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Engineering Transfusable Platelets for Improved Hemorrhage Control
Failure to control bleeding, such as during trauma and childbirth, accounts for more than half of all…
View details2024Competition
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Enhancement of melanoma chemosensitivity by adenoviral delivery of PUMA
Melanoma is an aggressive and lethal form of skin cancer that is increasingly prevalent among Caucasians. Although…
View details2004Competition
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