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The role of secreted protein acidic rich in cysteines (SPARC) in neurogenesis and gliogenesis in the embryonic and adult mouse brain: applications to models of Cerebral Ischemia Reperfusion Injury
Stroke is the primary cause of adult disability in Canada. Recovering brain function after stroke is dependent…
View details2008Competition
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The role of SHIP in normal and aberrant macrophage and osteoclast development and function
Michael Rauh believes the best approach to health research is to acquire insights from patients, and then…
View details2001Competition
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The role of SHIP in the development and function of myeloid immune suppressor cells
An important role of the immune system is to identify and eliminate tumour cells. When a tumour…
View details2008Competition
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The role of SHIP's C2 and PH domains in regulating hematopoietic cell growth and function
Various cancers and inflammatory diseases occur as a result of inappropriate activation of the body’s blood-forming hematopoietic…
View details2008Competition
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The role of social support in coping with chronic low back pain: help or hindrance?
Approximately 14 per cent of Canadians suffer from chronic low back pain, making it the second most…
View details2003Competition
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The role of specific genomic alterations in the aggressive nature of small cell lung cancer
Lung cancer remains the leading cause of cancer death for both men and women in Canada and…
View details2005Competition
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The role of the Ahi-1 oncogene in the regulation of hematopoietic stem cell development, function, and leukemogenesis
Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. The disease starts when genetic…
View details2011Competition
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The role of the airway epithelium NLRP3 inflammasome in asthma pathogenesis
Asthma is a respiratory disease that afflicts more than two million Canadians. Asthmatics experience both airway inflammation…
View details2011Competition
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The role of the DOG-1 helicase in repair of DNA interstrand cross-links in the model organism Caenorhabditis elegans
DNA damage repair pathways prevent cancer by recognizing and repairing DNA damage. If DNA damage is not…
View details2007Competition
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The role of the hematopoietic progenitor antigen, CD34 on mature mast cells
A study that Erin Drew took part in revealed some surprising insights about the mysterious CD34 protein.…
View details2001Competition
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The role of the innate immune system in hypoxic ischemic brain injury post cardiac arrest
In Canada, more than 50,000 cardiac arrest (i.e. “heart attack”) patients simultaneously suffer from brain injury due…
View details2022Competition
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The role of the integrin-linked kinase in intestinal inflammation
Affecting roughly one in 1,000 people in western populations, inflammatory bowel disease (IBD) includes both Crohn’s disease…
View details2002Competition
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