-
Antagonism of the p75 Neurotrophin Receptor promotes neurotrophin-mediated neural regeneration and plasticity within the injured spinal cord
Functional recovery following spinal cord injury is extremely limited, leaving individuals with limited mobility, autonomic dysfunction, and…
View details2006Competition
-
Anti-inflammatory cytokine function in individuals with type 2 diabetes: Impact of hyperglycemia and the restorative effects of exercise
Chronic low-grade inflammation (i.e. the persistent low-level production of pro-inflammatory factors by immune cells) is a major…
View details2021Competition
-
Antiangiogenesis-induced changes in the tumour microenvironment: a window for therapeutic exploitation in pancreatic cancer
Pancreatic cancer is the deadliest form of cancer, with an average life expectancy of three to six…
View details2008Competition
-
Antiarrhythmic drug effects on sodium channel slow-type inactivation – investigation of interactions at the selectivity filter
The selective passage of ions through channels in cellular membranes provides the molecular basis for many cellular…
View details2005Competition
-
Antibiotic Resistance in Superbugs: Regulation of the Blar beta-lactam sensor of MRSA and the MexAB-OprM multidrug-efflux effector PA3719 from Pseudomonas aeruginosa
Every year, Canada spends hundreds of millions of dollars in the fight against antibiotic-resistant “superbugs”, bacteria that…
View details2006Competition
-
Anticancer Drug Penetration into Solid Tumors
Solid tumours consist of a complex network of blood vessels surrounded by normal and malignant cells. They…
View details2001Competition
-
Application of Pleiades MiniPromoters for studying the role of NR2E1 in neural stem cells and mania-like behaviour
Severe psychiatric disorders affect three to five per cent of Canadians. One of these diseases is called…
View details2008Competition
-
Are there indicators of Alzheimer’s disease in the eye?: New computational imaging and analysis algorithms
Michael Smith Foundation for Health Research/The Pacific Alzheimer Research Foundation Post-Doctoral Fellowship Award Alzheimer’s disease (AD)…
View details2015Competition
-
Artificial intelligence based discovery of estrogen receptor activation function 2 (AF2) inhibitors as the first-in-class therapies for drug resistant breast cancers
Breast cancer (BCa) is the most common cancer and the second cause of death from cancer among…
View details2020Competition
-
Assembly of Postsynaptic Protein Complexes in Hippocampal Neurons
Synapses, the connections that enable brain cells to communicate with each other, are fundamental to normal brain…
View details2004Competition
-
Assembly of the type III secretion system in enteropathogenic E. coli and C. rodentium
Pathogenic E. coli bacteria cause severe intestinal infection and diarrhea in humans, leading to millions of cases…
View details2008Competition
-
Assessing Protective Factors for Self-harm: Development of the Barriers to Self-harm Inventory
Deliberate self-harm (DSH) is the deliberate, direct destruction of body tissue without suicidal intent. Common forms of…
View details2009Competition
Connect with us
We love to chat about our programs, activities and partnership opportunities. Don’t hesitate to reach out to us.
Contact us