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Developing a safe and effective analgesic for chronic pain relief
About 6 million Canadians report a form of chronic pain, yet half of the sufferers do not…
View details2019Competition
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Development and application of comprehensive T-cell receptor reactivity profiling technologies to aid in the discovery of novel immune cell therapies
The success of chimeric antigen receptor (CAR)-T cell therapy in the treatment of leukemia has spurred significant…
View details2020Competition
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Development of a novel biotherapeutic fusion protein inhibitor for treatment of advanced prostate cancer
Recent advances in targeted therapies have transformed the treatment of several types of cancer. Numerous agents, including…
View details2017Competition
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Development of a novel organ preservation solution in transplantation
There is a need to improve donor organ preservation strategies to meet donor organ requirements for transplantation.…
View details2017Competition
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DNA-PK inhibitors for use in combination with radiation therapy
Half of all cancer patients receive radiation therapy, impacting about seven million people worldwide each year. Enhancing…
View details2017Competition
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Engineered T regulatory cells to treat Crohn’s disease
Inflammatory bowel disease (IBD) is an incurable disease that affects about 230,000 Canadians. People with IBD suffer…
View details2018Competition
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eSense: an online psychological intervention for women’s health
Sexual dysfunction affects up to 1/3 of women across ages, cultures, and social conditions. The World Health…
View details2020Competition
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Fucosylation inhibitors for convenient production of fucose-deficient antibodies
Therapeutic antibodies have revolutionized the treatment of cancers. The efficacy of many of these antibodies depends on…
View details2020Competition
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Genomic Organization At Large (GOALS) predicts aggressive biological behaviour in prostate and breast cancers
Prostate cancer is the most commonly diagnosed form of cancer for men in North America. Prostate cancer…
View details2017Competition
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Improving cancer immunotherapy using G-CSF-blocking antibodies to overcome myeloid cell-mediated immunosuppression
Half of all Canadians will develop cancer and 1 in 4 will die of the disease. Cancer…
View details2019Competition
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Molecular classification for stratification and improved clinical management of endometrial cancers
In the current landscape of endometrial cancers (ECs), there is a shortfall in the management, treatment and…
View details2018Competition
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Multispectral RNA Mango: Synthesis of new multicolour fluorogens for incorporation into pathogen detection and identification kits
With the increasing prevalence of viral pathogens as exemplified by COVID-19, reliable and inexpensive detection is of…
View details2020Competition
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