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GlycoCaged N-heterocycles for improved treatment of inflammatory bowel diseases
Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is increasing in Canada and world-wide.…
View details2024Competition
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Human neuraminidase enzymes as therapeutic targets in skin inflammation
Chronic skin inflammation (CSI) includes two major groups of conditions: psoriasis, and atopic dermatitis (eczema) that, together,…
View details2024Competition
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Modulating Immune Cell Glycosylation as a Strategy to Improve the Anti-Tumor Response
Cancer cells develop ways of escaping and hiding from the immune system so that they are not…
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Regulating A Tumor-Specific Cell Surface Glycopeptide Epitope For Precision Immuno-Oncology
Unlike ‘liquid’ leukemias and lymphomas, most solid tumors are extremely difficult to target immunologically with antibody-based therapeutics.…
View details2024Competition
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Targeting Lipid Nanoparticles (LNPs) to Antigen-Presenting Cells Through Siglecs to Improve Vaccine Response and Durability
Vaccines can provide both short-term and long-term protection from deadly pathogens. This was demonstrated during the COVID19…
View details2024Competition
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Use of novel hybrid lectibodies to fight cryptococcosis
Fungal diseases affect more than a billion people worldwide, yet the responsible pathogens receive little attention and…
View details2024Competition
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