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The value of cardiac specific troponin in predicting cardiac outcomes in an asymptomatic chronic kidney disease population
Read moreChronic kidney disease is associated with a high risk for heart attack, even after accounting for traditional cardiac risk factors such as…
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Toxicogenetic analysis of valproic acid-associated hepatotoxicity in pediatric epileptic patients
Read moreValproic acid is a drug that has been used successfully for the treatment of many types of seizures. Yet for some patients,…
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Tracking the B-cell repertoire associated with the broadly-neutralizing antibody response in HIV-1 infection
Read moreThe progression from HIV infection to AIDS occurs because the body’s immune system fails to control replication of the virus. While broadly…
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2003
Translating mechanistic understanding of the systemic inflammatory response syndrome (SIRS) to clinical practice via genomics
Read moreEach year, about 75,000 patients in Canada will develop sepsis (severe infection). Although it is reversible, sepsis often causes death. Sepsis and…
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Truncation of huntingtin and its relationship to the pathogenesis of Huntington's Disease
Read moreHuntington disease (HD) is a fatal degenerative brain disorder caused by a defective gene, which causes cells in specific parts of the…
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Uncoupling dopamine and glutamine transmission in animal models of schizophrenia
Read moreSchizophrenia affects one per cent of Canadians — more than 300,000 people — causing personality and perceptual changes and thought disorders. Physical…
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Understanding low-income mothers' efforts to provide safe home environments for young children
Read moreUnintentional injuries represent the leading cause of death for children and youth under the age of 20. For children under five, approximately…
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Lise Olsen
Primary Investigator
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