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Design and Development of Novel Molecular Beacons for High-Precision T-Cell-Targeted mRNA and saRNA Delivery
Lipid nanoparticles (LNPs) are delivery vehicles approved for nucleic acid delivery, notably mRNA, as used in COVID…
View detailsPrimary Applicant:
Jonathan Dorogin
Supervisor:
Dr. Anna Blakney
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Elucidating and manipulating the role of the Unfolded Protein Response (UPR) to improve outcomes of stem cell-derived pancreatic islet transplants
Diabetes is a metabolic disorder characterized by the inability of patients to manage blood glucose levels because…
View detailsPrimary Applicant:
Austin Miller
Supervisor:
Dr. Francis Lynn
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Engineering human immune organoids to study next-generation Treg transplant therapies
Organ transplant patients need strong, lifelong medications to prevent their immune systems from rejecting the new organ,…
View detailsPrimary Applicant:
Romaniya Zayats
Supervisor:
Dr. Megan Levings
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Evaluating the Role and Therapeutic Value of MAP1B in Prostate Cancer
Prostate cancer (PCa) is commonly treated by blocking male hormone signaling through suppression of testosterone production or…
View detailsPrimary Applicant:
Yusuke Shiraishi
Supervisor:
Dr. Martin Gleave
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Examining the intersectional impacts of public health surveillance on racialized and migrant women living with HIV across the HIV Care Cascade in British Columbia
The HIV Care Cascade is a public health surveillance framework used to measure progress through HIV care…
View detailsPrimary Applicant:
Naomi Maldonado-Rodriguez
Supervisor:
Dr. Angela Kaida
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Extracellular Vesicle–Mediated Mechanisms and Therapeutic Targeting in Viral Myocarditis
Viral myocarditis is an inflammatory heart disease that can lead to heart failure or sudden death, especially…
View detailsPrimary Applicant:
Amirhossein Bahreyni
Supervisor:
Dr Honglin Luo
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Fallopian Screening for Tubo-Ovarian Cancer: Early Detection with Optical Imaging and Lavage
There are no effective screening tools for ovarian cancer, which is often found at late-stage. The most…
View detailsPrimary Applicant:
Jeanie Malone
Supervisor:
Dr. Calum MacAulay
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From Measurement to Action: Addressing Social Determinants of Health in Outpatient Cancer Treatment — A Mixed-Methods Study
Equitable access to cancer care is a major priority in Canada, but many patients face challenges that…
View detailsPrimary Applicant:
Amber Bourgeois
Supervisor:
Dr. Rick Sawatzky
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Frontline goblet cells: cellular drivers of barrier dysfunction in ulcerative colitis
Ulcerative colitis is a chronic, incurable inflammatory disease of the colon that can lead to lasting tissue…
View detailsPrimary Applicant:
Qiaochu Liang
Supervisor:
Dr. Kevan Jacobson
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How socio-structural inequities become embodied as health inequities: Examining pathways of gender inequities, inflammation and reproductive health outcomes among adolescent girls and young women
Bacterial vaginosis (BV) is highly prevalent among adolescent girls and young women (AGYW) in South Africa. AGYW…
View detailsPrimary Applicant:
Amanda Rowlands
Supervisor:
Dr. Angela Kaida
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Improving brain health in brain injury survivors through partner-oriented research: Can cognitive training increase brain neurotrophins, reduce inflammation, and improve cognitive performance?
Traumatic brain injury (TBI) affects many Canadians and can lead to long-term cognitive deficits affecting an individual’s…
View detailsPrimary Applicant:
Isla Shill
Supervisor:
Dr. Brian Christie
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Is fuel flexibility the key to making better stem cell-derived insulin secreting beta cells for type 1 diabetes therapy?
Pancreatic β cells produce insulin to control blood glucose. Loss of β cells results in type 1…
View detailsPrimary Applicant:
Alyssa Weinrauch
Supervisor:
Dr James Johnson