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Regulation and role of granzyme B in Atheromatous Diseases
Atherosclerosis – hardening of arteries – is caused by buildup of plaque inside artery walls. This constricts…
View details2003Competition
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Regulation of NMDA receptors and excitotoxicity
Glutamate mediates signaling between neurons (nerve cells) by binding to protein receptors. Over-activation of one type of…
View details2003Competition
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Regulation of thyroid hormone-dependent apoptosis and proliferation by the ING tumour suppressor
Thyroid hormones are critical for proper growth and development and are equally important in maintaining good health.…
View details2003Competition
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Retinoids in synovial sarcoma
Synovial sarcoma is a form of cancer occurring most commonly in the limbs of young adults. Patients…
View details2003Competition
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Synaptic and non-synaptic modulation of neuronal excitability
Neurons (nerve cells) communicate through a process in which one cell stimulates another with an electric pulse…
View details2003Competition
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Translating mechanistic understanding of the systemic inflammatory response syndrome (SIRS) to clinical practice via genomics
Each year, about 75,000 patients in Canada will develop sepsis (severe infection). Although it is reversible, sepsis…
View details2003Competition
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Use of T regulatory cells to induce tolerance to organ and tissue transplantation
Transplantation is the treatment of choice for many forms of end-stage organ failure and cancers of the…
View details2003Competition
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Airway epithelial injury as a result of corticosteroid-induced apoptosis
In people living with asthma, the cells lining the airway are more sensitive to injury from allergens…
View details2002Competition
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Cell therapies for the treatment of hematopoietic malignancies
Though small in numbers, stem cells are responsible for the continued production of blood cells throughout a…
View details2002Competition
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Central pathways mediating testosterone effects on hypothalamic responses to stress
The hypothalamic-pituitary-adrenal (HPA) axis is a brain-hormone system that plays an important role in the body’s reaction…
View details2002Competition
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Children’s mental health: Linking research evidence and policy making
How can we ensure that public policies in children's mental health reflect the best available research evidence…
View details2002Competition
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Community partnership research in population health promotion: The development of tools and measures for planning and evaluation
Strong evidence suggests that the health system is not the primary factor determining the health of Canadians.…
View details2002Competition
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