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Applications of bioorganic chemistry to medicine
Chemistry plays a central role in uncovering the mysteries of biology, and in the generation of new…
View details2006Competition
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Characterization of oligodendrocyte abnormalities in schizophrenia
Schizophrenia is a severe psychiatric illness affecting approximately one per cent of Canadians. While the causes are…
View details2006Competition
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Characterization of the influence of covalent histone modifications on DNA methylation in mammalian cells using a novel genomic targeting system
Normally, cells in the body grow, divide, and die in an orderly manner, under the direction of…
View details2006Competition
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Developing and using inhibitors to examine the role of O-GlcNac post-translational modification of proteins on glucohomeostasis and beta-cell adaptation
Type 2 diabetes develops when our bodies are unable to properly regulate blood glucose levels. Normally, blood…
View details2006Competition
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Endoplasmic reticulum-plasma membrane contact sites: Regulation of ER structure and cell growth
Lipids play important roles in all cells, separating the cell from the outside environment and serving to…
View details2006Competition
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Examination of the role of cadherin/beta-catenin adhesion complexes in the development and maintenance of synaptic junctions
Synapses of the central nervous system—junctions across which a nerve impulse passes from neuron to neuron—are highly-specialized…
View details2006Competition
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Functional dysconnectivity of hippocampo-prefrontal neural systems in Schizophrenia
Schizophrenia is a brain disease that affects one per cent of Canadians — more than 300,000 people…
View details2006Competition
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Gene and cell therapy approaches to treat diabetes
Transplantation of pancreatic islets has proven to be effective in controlling blood glucose levels in subjects with…
View details2006Competition
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Genome-scale variation in health and disease
The sophisticated approaches of genomics are increasingly being used to analyze the majority of the genetic material…
View details2006Competition
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Hormonal effects on neuroplasticity and behaviour
Contrary to popular belief, neurogenesis—the creation of new neurons—occurs in the adult brain in all species, including…
View details2006Competition
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Immunity and childhood disease
Immune white cells, such as cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, protect us from…
View details2006Competition
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Impact of nutrition and physical education school policies on childhood obesity: Understanding the implementation process and its impact on behavioural and weight outcomes
The prevalence of childhood obesity is rapidly increasing in Canada, increasing fivefold for both boys and girls…
View details2006Competition
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