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Characterizing the effects of cannabis smoking on airway epithelial cell reprogramming
Cannabis is the 2nd most used recreational drug in Canada, with 6 % of Canadians reporting daily…
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Exploring the Role of Granzyme B in Aging-Related Pruritus: Mechanisms and Therapeutic Potential
Itch, or chronic pruritus, is a common condition affecting about 40% of adults aged 65 and older.…
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Leveraging the native TCR with mRNA vaccines to enhance CAR T cell therapy in solid tumours.
The white blood cells known as T cells actively patrol the body for signs of pathogens or…
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Drug resistant CAR Tregs to promote transplant tolerance
Solid organ transplantation is often the last treatment option for people whose kidneys, liver, lungs, or heart…
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Origins and consequences of Persistent Low-Level HIV Viremia During Antiretroviral Therapy
Anti-HIV medications stop the virus from replicating in the body, prolonging life and preserving health. But, these…
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Reducing harms associated with ‘before medically advised’ hospital discharge
About 1 in 30 hospital patients leave the hospital before completing their treatment. These are known as…
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Targeting G Protein-Coupled Receptors to Improve Neurovascular Coupling in Alzheimer’s Disease
Alzheimer’s is a progressive disease that affects many Canadians. It causes problems with memory and thinking due…
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ACTIVE: Adding Life to Years in Cognitive Frailty by Preventing Falls and Promoting Cognitive Function
With age, some individuals experience physical frailty and difficulties in their thinking abilities (i.e., cognitive frailty). This…
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Alzheimer brain through 3D bioprinting patient-derived stem cells
Alzheimer’s disease (AD) is the leading cause of dementia, affecting over 55 million people worldwide. With no…
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Unraveling Apolipoprotein E’s Role in Alzheimer’s Disease: Insights into miRNA & Glial Regulation and Amyloid Pathology.
• Alzheimer’s disease (AD) is a brain disorder that some people develop as they age. It affects…
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Advancing the Health of Victim-Survivors of Sexual Assault: The Role of the Forensic Medical Examination
Sexual assault (SA) is traumatic and causes devastating health impacts such as post-traumatic stress disorder (PTSD), depression,…
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Exercise Snacks in Adults Living with Obesity
Individuals with obesity experience chronic low-grade inflammation increasing their risk of cardiometabolic disease. Inflammation is driven by…
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