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The role of Inflammatory bowel disease in the development of Alzheimer’s disease
People with inflammatory bowel disease (IBD) are six times as likely to develop Alzheimer’s disease and on…
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Air pollution as a modulator of molecular, structural, and clinical outcomes in patients with fibrotic interstitial lung disease
Interstitial lung diseases (ILDs) are serious conditions resulting in lung scarring, breathing difficulties, and a severely shortened…
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Cholesteryl ester transfer protein-mediated regulation of HDL cholesterol levels and clinical outcomes in sepsis
Sepsis is the overwhelming immune system response that occurs when someone develops a serious infection, and is…
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Cryo-EM studies of activators and inhibitors of KCNQ1 and KCNQ1:KCNE1 channel complexes
Type 1 Long QT syndrome (LQT1) and Short QT syndrome (SQT) result in life-threatening irregular heartbeats that…
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Fibrinogen promotes a microglial-mediated inflammatory response following adolescent repetitive mild traumatic brain injury
Concussions are a major health issue in Canada. Adolescents are an at-risk population for concussions because they…
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Pain and healthcare experiences of sex and gender minority citizens living with chronic pain in Canada
One in four people in Canada live with chronic pain. These individuals experience poorer health outcomes, higher…
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Predictive biomarkers for ovarian cancer treatment: Analysis of patient of derived xenografts under treatment at single cell resolution
Each year in Canada, around 3,000 women will be diagnosed with high grade serous ovarian cancer (HGSOC)…
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The association of genetic risk factors with morphology and outcomes in interstitial lung disease
Interstitial lung disease (ILD) is a diverse group of illnesses with a variety of causes. The current…
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Medulloblastoma plasma membrane proteomics to inform optimal immunotherapy design
Brain cancer is the most common pediatric solid cancer, devastating the lives of more than 5,000 children…
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Outcomes of a ketogenic dietary intervention on the gut microbiome-microglial brain axis and schizophrenia-like behaviour in mice exposed to a double-hit immune challenge
Alterations in microorganisms present in the gut are associated with various mental health disorders. It is possible…
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Regulation of anabolic metabolism in anti-tumour T cells
Our immune system protects of our body by detecting and destroying cells that are potentially cancerous. Sometimes,…
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