1 in 5 British Columbians will develop skin cancer. To detect cancer cells, a skin sample is typically removed surgically and studied through a microscope (known as histology). Unfortunately, this is invasive and has risks such as pain, infection, bleeding and scarring, which makes it impractical to perform repeatedly.
My research program focuses on using non-invasive optical imaging methods as an alternative to surgical biopsy, to provide microscopic views of the skin and to detect the presence of cancer cells. We will study 300 patients being treated for skin cancer and scan them to check for cancer cells at regular intervals. Through this, we will 1) evaluate how effective non-surgical treatments are for clearing cancer 2) study the behaviour of cancer cells after therapy and 3) compare optical findings to histology to confirm our results.
My research will offer a novel way of monitoring skin cancer, without undesired effects to the patient. This will improve cancer care by increasing our understanding of skin cancers, efficacy of treatments, and by guiding treatment to improve cure rates. This will provide crucial insights on how best to use less-invasive treatments and help improve patient experiences with cancer therapy.