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2025
Blocking the tumour-promoting effects of Fusobacterium nucleatum by eliciting an effective immune response against the tumour-binding Fap2 lectin
Read MoreThis Health Research BC and GlycoNet co-funded project focuses on Fusobacterium nucleatum (Fn), an oral gram-negative, anaerobic bacterium that can spread in…
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Robert A Holt
Primary Investigator
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Development and application of comprehensive T-cell receptor reactivity profiling technologies to aid in the discovery of novel immune cell therapies
Read MoreThe success of chimeric antigen receptor (CAR)-T cell therapy in the treatment of leukemia has spurred significant effort into developing similar “living…
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Robert A Holt
Primary Investigator
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2004
A novel approach to studying DNA copy number variation in schizophrenia and bipolar disorder
Read MoreSchizophrenia and bipolar disease are severe mental illnesses that affect thinking, mood and behaviour, and cause lifelong disability. Schizophrenia alone costs the…
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Robert A Holt
Primary Investigator
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